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1

Inhibition of interleukin-1α-induced cartilage oligomeric matrix protein degradation in bovine articular cartilage by matrix metalloproteinase inhibitors: Potential role for matrix metalloproteinases in the generation of cartilage oligomeric matrix protein fragments in arthritic synovial fluid

Vishwas Ganu, Ronald Goldberg, Jane Peppard, John Rediske, Richard Melton, Shou-Ih Hu, Weigwang Wang, Charlotte Duvander, Dick Heinegård

Journal:

Arthritis & Rheumatism

Année:

1998

Langue:

english

Fichier:

PDF, 918 KB

english, 1998

2

ChemInform Abstract: Design and Synthesis of Thiol Containing Inhibitors of Matrix Metalloproteinases.

Cynthia A. Fink, J. Eric Carlson, Charles Boehm, Patricia McTaggart, Ying Qiao, John Doughty, Vishwas Ganu, Richard Melton, Ronald Goldberg

Journal:

Année:

1999

Fichier:

PDF, 31 KB

1999

3

Characterization of Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2, a fluorogenic substrate with increased specificity constants for collagenases and tumor necrosis factor converting enzyme

Ulf Neumann, Hisashi Kubota, Karl Frei, Vishwas Ganu, David Leppert

Journal:

Analytical Biochemistry

Année:

2004

Langue:

english

Fichier:

PDF, 548 KB

english, 2004

4

Design and synthesis of thiol containing inhibitors of matrix metalloproteinases

Cynthia A. Fink, J.Eric Carlson, Charles Boehm, Patricia McTaggart, Ying Qiao, John Doughty, Vishwas Ganu, Richard Melton, Ronald Goldberg

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1999

Langue:

english

Fichier:

PDF, 255 KB

english, 1999

5

A novel tricyclic pyrazine from lysine hydrochloride pyrolysis

Vishwas S. Ganu, Arthur L.Y. Lau, Harry H. Wasserman

Journal:

Tetrahedron Letters

Année:

1980

Langue:

english

Fichier:

PDF, 114 KB

english, 1980

6

Matrix Metalloproteinase Inhibitor CGS 27023A Protects COMP and Proteoglycan in the Bovine Articular Cartilage but not the Release of Their Fragments from Cartilage after Prolonged Stimulation in Vitro with IL-1α

VISHWAS GANU, RICHARD MELTON, WEIGWANG WANG, DON ROBERTS

Journal:

Annals of the New York Academy of Sciences

Année:

1999

Langue:

english

Fichier:

PDF, 585 KB

english, 1999

7

Potent and selective 2-naphthylsulfonamide substituted hydroxamic acid inhibitors of matrix metalloproteinase-13

Ruben A. Tommasi, Sven Weiler, Leslie W. McQuire, Olivier Rogel, Mark Chambers, Kirk Clark, John Doughty, James Fang, Vishwas Ganu, Jonathan Grob, Ronald Goldberg, Robert Goldstein, Stacey LaVoie, Rav

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2011

Langue:

english

Fichier:

PDF, 1017 KB

english, 2011

8

Synthesis and properties of cyclic peptides containing the activation site of plasminogen

VISHWAS S. GANU, ELLIOTT SHAW

Journal:

Chemical Biology & Drug Design

Année:

1982

Langue:

english

Fichier:

PDF, 555 KB

english, 1982

9

Solution structure of the catalytic domain of human collagenase-3 (MMP-13) complexed to a potent non-peptidic sulfonamide inhibitor: binding comparison with stromelysin-1 and collagenase-1

Xiaolu Zhang, Nina C Gonnella, James Koehn, Naveen Pathak, Vishwas Ganu, Richard Melton, David Parker, Shu-Ih Hu, Ki-Yean Nam

Journal:

Journal of Molecular Biology

Année:

2000

Langue:

english

Fichier:

PDF, 517 KB

english, 2000

10

Factor C3f is a spasmogenic fragment released from C3b by factors I and H: The heptadeca-peptide C3f was synthesized and characterized

Vishwas S. Ganu, Hans J. Müller-Eberhard, Tony E. Hugli

Journal:

Molecular Immunology

Année:

1989

Langue:

english

Fichier:

PDF, 1.17 MB

english, 1989

11

Thick filter neutrophil chemotaxis performed in the absence of albumin

Stacy Psychoyos, Susan Uziel-Fusi, Michael M. Morrissey, Vishwas Ganu, C. Wayne Smith

Journal:

Journal of Immunological Methods

Année:

1991

Langue:

english

Fichier:

PDF, 775 KB

english, 1991

12

Improved synthetic inactivators of plasmin

Vishwas S. Ganu, Elliott Shaw

Journal:

Thrombosis Research

Année:

1987

Langue:

english

Fichier:

PDF, 431 KB

english, 1987

13

Discovery of Potent, Selective, and Orally Active Carboxylic Acid Based Inhibitors of Matrix Metalloproteinase-13 †

Monovich, Lauren G., Tommasi, Ruben A., Fujimoto, Roger A., Blancuzzi, Vincent, Clark, Kirk, Cornell, Wendy D., Doti, Robert, Doughty, John, Fang, James, Farley, David, Fitt, John, Ganu, Vishwas, Gold

Journal:

Journal of Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2009

14

Mapping of the C3d Receptor (CR2)-Binding Site and a Neoantigenic Site in the C3d Domain of the Third Component of Complement

John D. Lambris, Vishwas S. Ganu, Shirish Hirani and Hans J. Müller-Eberhard

Journal:

Proceedings of the National Academy of Sciences

Année:

1985

Langue:

english

Fichier:

PDF, 793 KB

english, 1985

15

HIV-1 Transactivator Protein Tat Induces Proliferation and TGFβ Expression in Human Articular Chondrocytes

Martin Lotz, Ian Clark-Lewis and Vishwas Ganu

Journal:

The Journal of Cell Biology

Année:

1994

Langue:

english

Fichier:

PDF, 369 KB

english, 1994

16

Epoxide hydrase: structure-activity relationships of in vitro stimulators of the microsomal activity

Ganu, Vishwas S., Alworth, William L.

Journal:

Année:

1978

Langue:

english

Fichier:

PDF, 785 KB

english, 1978

17

Inactivation of trypsin-like proteases by depsipeptides of p-guanidinobenzoic acid

Ganu, Vishwas S., Shaw, Elliott

Journal:

Journal of Medicinal Chemistry

Année:

1981

Langue:

english

Fichier:

PDF, 458 KB

english, 1981

18

Solution Structure of the Catalytic Domain of Human Stromelysin-1 Complexed to a Potent, Nonpeptidic Inhibitor

Li, Yu-Chin, Zhang, Xiaolu, Melton, Richard, Ganu, Vishwas, Gonnella, Nina C.

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 147 KB

english, 1998

19

Bioactive Conformation of Stromelysin Inhibitors Determined by Transferred Nuclear Overhauser Effects

Nina C. Gonnella, Regine Bohacek, Xiaolu Zhang, István Kolossváry, C. Gregory Paris, Richard Melton, Cindy Winter, Shou-Ih Hu and Vishwas Ganu

Journal:

Proceedings of the National Academy of Sciences

Année:

1995

Langue:

english

Fichier:

PDF, 1.18 MB

english, 1995

20

Elevation of plasma hyaluronan and urinary pyridinoline in mouse collagen induced arthritis

Goldberg, Ronald L, Ganu, Vishwas S, Kotyuk, Bernard, Doughty, John R, Raychaudhuri, Anil

Journal:

Acta Orthopaedica Scandinavica

Année:

1995

Fichier:

PDF, 464 KB

1995